Preconditioning of the response to ischemia/reperfusion-induced plasma leakage in hamster cheek pouch microcirculation

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Preconditioning of the response to ischemia/reperfusion-induced plasma leakage in hamster cheek pouch microcirculation

OBJECTIVE Ischemic preconditioning and some drugs can protect tissues from injury by preserving microcirculation. This study evaluated vascular permeability in a hamster cheek pouch preparation using either short ischemic periods or bradykinin as preconditioning stimuli followed by 30 min of ischemia/reperfusion. METHOD Sixty-six male hamsters were divided into 11 groups: five combinations of...

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Gender differences in microcirculation: Observation using the hamster cheek pouch

OBJECTIVES Estrogen has been shown to play an important protective role in non-reproductive systems, such as the cardiovascular system. Our aim was to observe gender differences in vivo with regard to the increase in macromolecular permeability and leukocyte-endothelium interaction induced by ischemia/reperfusion as well as in microvascular reactivity to vasoactive substances using the hamster ...

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Melatonin prevents ischemia reperfusion injury in hamster cheek pouch microcirculation.

OBJECTIVE We used the hamster cheek pouch microcirculation to investigate the effects of melatonin (ME) on ischemia reperfusion (I-R) injury by in vivo microscopy. ME is a hormone produced by the pineal gland and is the most powerful and effective hydroxyl radical scavenger detected to date in vitro. The second aim was to determine the scavenger effect of ME in cheek pouch microcirculation when...

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ژورنال

عنوان ژورنال: Clinics

سال: 2012

ISSN: 1807-5932

DOI: 10.6061/clinics/2012(08)12